by Alex Kadhim
Graft-versus-host disease (GvHD) remains a challenge in the realm of allogeneic hematopoietic cell transplantation (allo-HCT), with the choice of prophylaxis strategy playing a critical role in...
by Blood Advances
Based on promising results with third-party fecal microbiota transplantation (FMT), scientists are urged to explore microbiome-targeted interventions as an early treatment for acute...
by Cell Reports Medicine
A novel co-targeting design promises to heighten the effects of chimeric antigen receptor (CAR) T-cell activity in certain B-cell lymphoma patients, a population that can benefit from CAR...
by Clinical Cancer Research
Mesothelin-directed chimeric antigen receptor (CAR) T-cells have had only limited success in treating pancreatic ductal adenocarcinoma (PDAC), but researchers have uncovered a strategy to overcome...
by Alex Kadhim
An analysis of secondary outcomes from the KarMMA-3 trial (NCT03651128) have recently been published in the journal Lancet Hematology.
by The New England Journal of Medicine
Chimeric antigen receptor (CAR) T-cell therapy could have a future role in managing autoimmune disorders, based on emerging evidence. Researchers suspected ablation of B cells might...